AC Milan has cancelled today's scheduled match in Lombardy because of the coronavirus.
Inter Milan also confirmed on Twitter the postponement of Sunday's game at AC Milan's San Siro stadium.
All sporting events will be suspended on Sunday in Lombardy because the killer virus has claimed two lives in Italy, the club said.
In a tweet the AC Milan said: "Due to the Coronavirus outbreak, all sporting events in Lombardy have been called off including Rossonere's clash."
Meanwhile Inter Milan Tweeted: "InterSampdoria, which was due to take place at 20:45 CET on Sunday 23 February, has been postponed to a later date."
Milan Women's team were due to take on Fiorentina in a home game.
Inter Milan's game against Sampdoria is among three other fixtures which are postponed over fears of the spread of coronavirus.
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The game suspensions also includes Verona v Cagliari and Atalanta v Sassuolo.
It comes as a woman in the Lombardy region is the second person to die from coronavirus in Italy, forcing parts of the country into lockdown.
Italian authorities said the number of people infected with the new coronavirus from China has more than quadrupled due to an emerging cluster of cases in the country's north.
Many of the new cases represented the first infections in Italy acquired through secondary contagion and brought the country's total to 17.
The first to fall ill in northern Italy met with someone who had returned from China on January 21 without presenting any symptoms of the new virus, called Covid-19, health authorities said.
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The 38-year-old Italian man is in hospital in the northern town of Codogno in a critical condition.
The man's wife and a friend of his also tested positive for the virus.
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Three patients at the hospital where he went with flu-like symptoms a few days ago also have infections.
Five nurses and doctors contracted the virus as well.
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